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28 June 2026

Raman-DIP technique for TB drug resistance

This technique represents a significant advancement in medical diagnostics for a major public health challenge in India, providing useful context for questions on biotechnology applications and healthcare technology.

1 min read 1 questions 1 prelims

Notes

  • Raman-DIP is a new diagnostic technique developed to test drug resistance in Mycobacterium tuberculosis.
  • Traditional phenotypic testing methods require 4 to 8 weeks for bacterial culture and multiplication.
  • Raman-DIP utilizes single-cell imaging to monitor the metabolic processing of heavy water by bacteria.
  • The technique identifies antibiotic inhibition of bacterial growth within 50 hours.
  • The method has demonstrated 100% accuracy in testing against four major anti-TB drugs across various bacterial strains.

Questions

  1. Discuss the significance of rapid diagnostic technologies like Raman-DIP in addressing the challenge of drug-resistant tuberculosis in India. How can such innovations strengthen the public health response to communicable diseases? 150 words
    Attempt this — 150 words in 8 min
    0 / 150 words 8:00

Prelims

  1. The 'Raman-DIP' technique, recently in the news, is associated with which of the following?